Compared with ontogenetical changes during growth consist in the fusion and greater robustness of the skeletal elements.
2.
SCO-spondin may interfere with several biological events during early ontogenetical development of the CNS . Nevertheless, SCO-spondin is also present during the adult life, and similarly to thrombospondins, which act on various biological systems, i . e ., neuronal differentiation, angiogenesis and platelet aggregation.
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