| 1. | Pentamidine is primarily metabolized by Cytochrome P450 enzymes in the liver.
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| 2. | When injected, pentamidine binds to tissues and proteins in the plasma.
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| 3. | Up to 12 % of pentamidine is eliminated in the urine unchanged.
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| 4. | Drug of choice is Trimethoprim / sulfamethoxazole, pentamidine, or dapsone.
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| 5. | Inhaled pentamidine is mainly deposited into the bronchoalveolar lavage fluid of the lungs.
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| 6. | Pentamidine is useless for these people.
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| 7. | Pentamidine can remain in the system for as long as 8 months after the first injection.
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| 8. | In desperation, we gambled on pentamidine, an antiparasitic drug we had in the hospital pharmacy.
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| 9. | But in late 1980 a small but growing number of doctors began requesting pentamidine for their patients.
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| 10. | Pentamidine is less often used as its major limitation is the high frequency of low blood sugar.
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