| 1. | All patients had previously not responded to an antiarrhythmic drug called procainamide.
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| 2. | Also it binds 10 % less to proteins than procainamide.
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| 3. | Procainamide, quinidine and disopyramide are Class Ia agents.
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| 4. | Also procainamide-induced antinuclear antibodies are formed after a 6 months treatment.
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| 5. | Chemically, it is the " N "-acetylated metabolite of procainamide.
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| 6. | This substitution is the reason why procainamide exhibit a longer half-life time than procaine.
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| 7. | It is a Class III antiarrhythmic agent, whereas procainamide is a Class Ia antiarrhythmic drug.
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| 8. | Oral procainamide is no longer being manufactured in the US, but intravenous formulations are still available.
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| 9. | Procainamide is structurally similar to procaine but in place of an ester group contains procainamide an amide group.
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| 10. | Procainamide is structurally similar to procaine but in place of an ester group contains procainamide an amide group.
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