It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160.
3.
Human renin is secreted by at least 2 cellular pathways : a constitutive pathway for the secretion of the precursor prorenin and a regulated pathway for the secretion of mature renin.
4.
:Hydrolyses mouse Ren2 protein ( a species of prorenin present in the submandibular gland ) on the carboxy side of the arginine residue at the Lys-Arg-pair in the N-terminus, to yield mature renin
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