prostacyclin वाक्य
उदाहरण वाक्य
मोबाइल
- The unqualified term'prostacyclin'usually refers to PGI 2.
- Treprostinil is a synthetic analog of prostacyclin ( PGI 2 ).
- PGE2 and prostacyclin inhibit platelet aggregation and dilate blood vessels.
- Examples of animal hormones subjected to ion trapping include Prostacyclin and Leukotrienes.
- This highly unstable compound is rapidly transformed into other prostaglandins, prostacyclin and thromboxanes.
- It is classified as a prostacyclin analog.
- Synthetic pathways from PGH 2 ( the parent compound ) to prostaglandins, prostacyclin and thromboxanes
- It does not stimulate as much prostacyclin and NO to induce relaxation on smooth muscle cells.
- Instead it uses its heme cofactor to catalyze the isomerization of prostaglandin H 2 to prostacyclin.
- Today's pulmonary hypertension treatment, prostacyclin, is proved to extend many patients'lives.
- The Nobel committee cited Vane for discovering prostacyclin and carrying out detailed analyses of its biological effects and function.
- This intravenous prostacyclin relaxes blood vessels and buys an extra five years of life for about 60 percent of patients.
- The loss of this source of prostacyclin could help explain why women who have had hysterectomies are prone to cardiovascular problems.
- The 5-carbon ring of prostacyclin is conjoined to a second ring consisting of 4 carbon and one oxygen atom.
- Prostacyclin usually prevents platelet aggregation and vasoconstriction, so its inhibition can lead to excess clot formation and higher blood pressure.
- Apo A1 was also isolated as a prostacyclin ( PGI2 ) stabilizing factor, and thus may have an anticlotting effect.
- But like native prostacyclin, the structure of the epoprostenol molecule proved to be unstable in solution, prone to rapid degradation.
- The intravenous drug, called Flolan, or prostacyclin, buys an extra five years of life for about 60 percent of patients.
- Prostacyclin falls into a category of compounds known as prostaglandins, which help the cells defend against sudden changes from injury, disease or stress.
- Dysregulation of TXA synthase and an imbalance in the prostacyclin-thromboxane ratio are thought to underlie many pathological conditions, such as pulmonary hypertension.
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