| 1. | Pseudocholinesterase deficiency may also affect local anaesthetic selection in dental procedures.
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| 2. | Inheriting abnormal pseudocholinesterase ) may affect metabolism of drugs such as succinylcholine
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| 3. | Clevidipine will still be rapidly metabolized in pseudocholinesterase-deficient patients.
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| 4. | The first in pharmacogenetics was concerned with the genetics and biochemistry of pseudocholinesterase.
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| 5. | The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical.
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| 6. | Finally, pseudocholinesterase metabolism of procaine results in formation of paraaminobenzoic acid ( PABA ).
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| 7. | Two pools of cholinesterases exist in the blood : acetylcholinesterase in erythrocytes and pseudocholinesterase in plasma.
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| 8. | Metabolism can therefore be very slow in people with pseudocholinesterase deficiency, resulting in prolonged paralysis.
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| 9. | An absence or mutation of the BCHE enzyme leads to a medical condition known as pseudocholinesterase deficiency.
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| 10. | This enzyme abnormality is a benign condition unless a person with pseudocholinesterase deficiency is exposed to the offending pharmacological agents.
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