| 11. | Glutamate racemase performs the additional function of gyrase inhibition, preventing gyrase from binding to DNA.
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| 12. | The ability of gyrase to relax positive supercoils comes into play during DNA replication and prokaryotic transcription.
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| 13. | DNA Gyrase is an enzyme used to unwind double stranded DNA which is essential to DNA Replication.
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| 14. | The eukaryotic topo II, bacterial gyrase, and bacterial topo IV belong to the type II.
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| 15. | Confusion arises when some scientific literature state that DNA gyrase is the sole enzyme responsible for decatanation.
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| 16. | Mutations in DNA gyrase are commonly associated with antibiotic resistance in " P . aeruginosa ".
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| 17. | While antibacterial compounds such as ciprofloxacin target bacterial gyrase, they fail to inhibit eukaryotic type IIA topoisomerases.
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| 18. | In this particular experiment, when DNA gyrase alone were inhibited, most of the catenanes were unlinked.
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| 19. | Fourth generation fluoroquinolones act at DNA gyrase and topoisomerase IV . This dual action slows development of resistance.
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| 20. | It is responsible for killing plasmid-free segregants, and interferes with the activity of DNA gyrase.
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