Some studies have shown that in individuals over 70 years of age, micronucleus frequency increases in both sexes.
12.
Although the micronucleus model is appropriate, other factors are likely to contribute towards chromothripsis for various cancer genomes.
13.
Since micronucleus assays reflect chromosomal aberrations reliably and rapidly, they are extremely useful for a quick assessment of chromosomal damage.
14.
In mice, these are not removed, which is the basis for the " in vivo " micronucleus test.
15.
Fewer than expected homozygous mutant mice survived until weaning and those that did survive displayed evidence of chomosomal instability in a micronucleus test.
16.
The micronucleus is the generative, or germline nucleus, containing the genetic material that is passed along from one generation to the next.
17.
Twenty six tests were carried out on mutant mice and one significant abnormality was observed : chromosomal instability was detect by a micronucleus test.
18.
Based on the structure of a Micronucleus, or the function of a cell, it provides support in the central apparatus within the cell.
19.
Micronucleus assay systems are very economical, require much less skill in scoring that conventional metaphase tests, and are much faster than these conventional tests.
20.
The ciliated protozoan Tetrahymena is a useful research model for studying nuclear dimorphism; it maintains two distinct nuclear genomes, the micronucleus and the macronucleus.
