| 11. | With the sealing zone in place, the multinucleated osteoclast reorganizes itself.
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| 12. | In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation.
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| 13. | RANKL is a main factor of the differentiation of osteoclasts.
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| 14. | Attachment of the osteoclast to the osteon begins the process.
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| 15. | Continued elevation of PTH levels increases the abundance of osteoclasts.
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| 16. | The last reason that osteoclasts are used is for growing.
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| 17. | Activation of these genes results in robust osteoclast formation and bone loss.
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| 18. | The reabsorption of bone by osteoclasts also plays a role in calcium homeostasis.
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| 19. | Carbonic anhydrase is required by osteoclasts for proton production.
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| 20. | Bones are made of cells called osteoclasts and osteoblasts.
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