Other drugs used for ventricular arrhythmia include lidocaine, amiodarone, bretylium, flecainide, procainamide, and mexiletine.
12.
People with atrial fibrillation and rapid ventricular response are often treated with amiodarone or procainamide to stabilize their heart rate.
13.
Also procainamide can be acetylated to acecainide and to other reactive and toxic metabolites, which would contradict the efficacy.
14.
"' Procainamide "'is a medication of the antiarrhythmic class used for the treatment of cardiac arrhythmias.
15.
To have a high efficacy, the antiarrhythmic drug procainamide has to be dosed frequently to maintain an adequate serum concentration.
16.
It is only partially as active as procainamide; when checking levels, both must be included in the final calculation.
17.
But further research showed, that after a long-term therapy of procainamide, some subjects did not produce any antinuclear antibodies.
18.
Brodie also did research on anesthetic and hypnotic drugs and discovered that procainamide was effective in treating patients with severe irregularities in heart rhythm.
19.
Both propoxyphene and norpropoxyphene are potent blockers of cardiac membrane sodium channels and are more potent than lidocaine, quinidine, and procainamide in this respect.
20.
Procainamide is a classical bioisostere because the valence electron structure of a disubstituted oxygen atom is the same as a trisubstituted nitrogen atom, as Langmuir showed.
