| 11. | Stimulated by a severe epidemic, variolation was first employed in North America in 1721.
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| 12. | But people undergoing variolation felt well enough to be out and about _ while fully contagious.
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| 13. | To create immunity, Americans turned to variolation, in which smallpox was inserted through the skin.
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| 14. | A very early form of vaccination known as variolation was developed several thousand years ago in China.
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| 15. | The patriarch Robert Sutton was a surgeon from Suffolk who began experimenting with the practice of variolation.
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| 16. | The simplest debate argued that variolation was ungodly because it was not mentioned specifically in the Bible.
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| 17. | Its implementation at the time was impractical for logistical reasons and the risk that variolation would spread smallpox.
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| 18. | The term " variolation " was then used from the 19th century to avoid confusion with vaccination.
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| 19. | The use of variolation soon began to decline as the smallpox vaccine became widely used and its benefits appreciated.
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| 20. | The variolation available to the rich ended up making things worse for those who could not afford to buy immunity.
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