Two enantiomers of anatoxin-a, the positive enantiomer, ( + ) anatoxin-a, is 150 fold more potent than the synthetic negative enantiomer, ( " ) anatoxin-a.
22.
Two enantiomers of anatoxin-a, the positive enantiomer, ( + ) anatoxin-a, is 150 fold more potent than the synthetic negative enantiomer, ( " ) anatoxin-a.
23.
Two enantiomers of anatoxin-a, the positive enantiomer, ( + ) anatoxin-a, is 150 fold more potent than the synthetic negative enantiomer, ( " ) anatoxin-a.
24.
Once it has triggered a contraction, anatoxin-" a " does not allow the neurons to return to their resting state, because it is not degraded by cholinesterase which normally performs this function.
25.
There is continued interest in anatoxin-" a " because of the dangers it presents to recreational and drinking waters, and because it is a particularly useful molecule for investigating acetylcholine receptors in the nervous system.
26.
Investigations into anatoxin-" a ", also known as " Very Fast Death Factor ", began in 1961 following the deaths of cows that drank from a lake containing an algal bloom in Saskatchewan, Canada.
27.
Symptoms of anatoxin exposure include anatoxin-a ( S ), another potent cyanotoxin that has a similar mechanism of action to that of anatoxin-a and is produced by many of the same cyanobacteria genera, but is structurally unrelated.
28.
Symptoms of anatoxin exposure include anatoxin-a ( S ), another potent cyanotoxin that has a similar mechanism of action to that of anatoxin-a and is produced by many of the same cyanobacteria genera, but is structurally unrelated.
29.
Symptoms of anatoxin exposure include anatoxin-a ( S ), another potent cyanotoxin that has a similar mechanism of action to that of anatoxin-a and is produced by many of the same cyanobacteria genera, but is structurally unrelated.
30.
Injections of mice, rats, birds, dogs, and calves with lethal doses of anatoxin-a have demonstrated that death is preceded by a sequence of muscle fasciculations, decreased movement, collapse, exaggerated abdominal breathing, cyanosis and convulsions.
