The breed can also fall victim to progressive retinal atrophy ( a degeneration of the retina causing blindness ) and several less serious hereditary eye problems such as coloboma ( a hole in the eye structure ), and persistent pupillary membrane ( tiny threads across the pupil ).
22.
At only 13 months old he was diagnosed with unilateral coloboma, meaning the condition only affects one eye, at that time Cl�ment was only given a 40 / 60 % chance of having healthy eyesight for the rest of his life, throughout his tennis career Cl�ment has worn sunglasses to protect his eyes.
23.
The cranial dysmorphisms associated with 3C syndrome are heterogeneous and include a degree of macrocephaly, a large anterior fontanel, a particularly prominent occiput and forehead, ocular hypertelorism ( wide-set eyes ), slanted palpebral fissures, cleft palate, a depressed nasal bridge, cleft palate with associated bifid uvula, Low-set ears are the most common cranial dysmorphism seen in 3C syndrome, and ocular coloboma is the least common of the non-concurrent symptoms ( cleft lip co-occurring with cleft palate is the least common ).
