*" AIDS-associated Kaposi sarcoma " typically presents with cutaneous lesions that begin as one or several red to purple-red macules, rapidly progressing to papules, plaques, with a predilection for the head, back, neck, trunk, and mucous membranes.
22.
Inactivating mutations in TMC6 or TMC8 have been implicated as the genetic cause of the rare skin disorder epidermodysplasia verruciformis, which is characterized by abnormal susceptibility to human papillomaviruses ( HPVs ) of the skin resulting in the growth of scaly macules and papules, particularly on the hands and feet.
23.
Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion ( s ), including the location ( such as arms, head, legs ), symptoms ( pruritus, pain ), duration ( acute or chronic ), arrangement ( solitary, generalized, annular, linear ), morphology ( macules, papules, vesicles ), and color ( red, blue, brown, black, white, yellow ).
24.
As identified in this first case study and stated in a dictionary of dermatologic syndromes, ABCD syndrome has many notable features, including snow white hair in patches, distinct black locks of hair, skin white except brown macules, deafness, irises gray to blue, nystagmus, photophobia, poor visual activity, normal melanocytes in pigmented hair and skin, and absent melanocytes in areas of leukoderma . Individuals have the blue / gray irises typical of people affected by blindness.
