| 21. | Therefore, hirudin prevents or dissolves the formation of clots and complexed thrombin.
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| 22. | In fact, it inhibits thrombin by affecting ATIII.
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| 23. | It does not inhibit ?-chymotrypsin or thrombin.
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| 24. | F2RL2 is a cofactor for F2RL3 activation by thrombin.
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| 25. | Furthermore, the complex can be activated by thrombin.
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| 26. | After thrombin activation, the mature protein downregulates fibrinolysis.
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| 27. | Allosteric inhibitors of thrombin have been discovered which could potentially be used as anticoagulants.
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| 28. | Blood from a ruptured cerebral aneurysm clots around a cerebral artery, releasing thrombin.
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| 29. | In 2013 a system for detecting the presence of thrombin was developed in mice.
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| 30. | Factor Xa ( in the presence of factor V ) activates prothrombin into thrombin.
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