The main forerunners of the English variolation movement were the Suttons, a family of physicians who would revolutionize the practice of variolation.
32.
The term " variolation " refers solely to inoculation with smallpox virus and is not interchangeable with " vaccination ".
33.
By the end of the American Revolutionary War, variolation had gained widespread acceptance in the larger cities and towns of the United States.
34.
Several historians have suggested that variolation may be older than the eighteenth century in India, but historical evidence for this assertion is lacking.
35.
Because of its greater risks, variolation was banned in England by the 1840 Vaccination Act, which also introduced free voluntary vaccination for infants.
36.
Jenner's method was soon shown to be safer than variolation, and by 1801 more than 100, 000 people had been vaccinated.
37.
To avoid confusion, smallpox inoculation was increasingly referred to as variolation, and it became common practice to use this term without regard for chronology.
38.
This method of immunisation parallels variolation, an early form of human vaccination, which used live pathogens to protect patients against, for example, smallpox
39.
No one knows why variolation works, but it produces a mild form of smallpox with a fatality rate of only 1 percent instead of 30 percent.
40.
In February 1777 while encamped at Morristown, New Jersey, Washington became convinced that only smallpox inoculation by variolation would prevent the destruction of his Army.
