| 41. | Narlaprevir does not bind to human proteases, with the exception of cathepsin B ( 69 % inhibition ).
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| 42. | Cathepsin S participates in the degradation of the invariant or Ii chain that prevents loading the antigen into the complex.
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| 43. | Cathepsin Z has been shown to MSN, MTUS2, NOTCH2NL, PLK2, PLSCR1, SGOL2, and SPRED2.
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| 44. | Very small amounts of enzymatic activity can be elucidated and is capable of resolving a femtomole of cathepsin K activity.
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| 45. | There are, however, exceptions such as cathepsin K, which works extracellularly after secretion by osteoclasts in bone resorption.
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| 46. | Cathepsin K is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness.
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| 47. | The translated prepro-cathepsin C is processed into the mature form by at least four cleavages of the polypeptide chain.
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| 48. | Cathepsin D "'is a protein that in humans is encoded by the " CTSD " gene.
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| 49. | The main function of cathepsin D is to degrade proteins and activate precursors of bioactive proteins in pre-lysosomal compartments.
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| 50. | This disease is due to mutations in the CTSA gene which encodes the protective protein / cathepsin A ( PPCA ).
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