| 41. | Its catalytic site involves sulfohydryl group of Cys-285 and the imidazole ring of its His-237.
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| 42. | "' Imidazole "'is an organic compound with the formula C 3 N 2 H 4.
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| 43. | The name " imidazole " was coined in 1887 by the German chemist Arthur Rudolf Hantzsch ( 1857 1935 ).
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| 44. | Several rings contain basic as well as non-basic nitrogen atoms, e . g . imidazole and purine.
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| 45. | In such model complexes, the Tp " simulates the coordination environment provided by three imidazole ligands in proteins.
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| 46. | 2-Methylimidazole is a sterically hindered imidazole that is used to similuate the coordination of histidine to heme complexes.
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| 47. | This is potentially due to a lead lone pair of electrons, also found in lead complexes with an imidazole ligand.
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| 48. | Imidazole is used to elute tagged proteins bound to nickel ions attached to the surface of beads in the chromatography column.
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| 49. | Modification of histidine by DEPC results in carbethoxylated derivates at the N-omega-2 nitrogen of the imidazole ring.
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| 50. | Ketoconazole is an imidazole derivative is used as a broad-spectrum antifungal agent effective against a variety of fungal infections.
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