| 41. | *Osteoclasts are the cells responsible for bone resorption, thus they break down bone.
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| 42. | In space, however, there is an increase in osteoclast activity due to microgravity.
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| 43. | The brown tumors commonly associated with OFC display many of the same characteristics of osteoclasts.
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| 44. | Osteoclasts are generally present on the outer layer of bone, just beneath the periosteum.
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| 45. | Upon partial dephosphorylation, both osteopontin and bone sialoprotein are incapable of binding to osteoclasts.
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| 46. | AE2 is required for normal osteoclast function.
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| 47. | Recent research suggests that kahweol may have beneficial effects on bone by inhibiting osteoclast differentiation.
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| 48. | Mantyh said the osteoclasts also seem to hypersensitize nerves which carry pain stimuli to the brain.
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| 49. | The osteoblast cell forms new bone, while osteoclast dissolves old and worn out bone tissue.
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| 50. | For example, the rate at which osteoclasts resorb bone is inhibited by calcitonin and osteoprotegerin.
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