It is proposed that LTD in GABAergic striatal neurons leads to a long term decrease in inhibitory effects on the basal ganglia, influencing the storage of motor skills.
42.
Additionally, the anterior parietal activity showed a relationship with caudate functioning, which implicates a compensatory mechanism set forth when damage to the fronto-striatal system occurs.
43.
Blocking the endogenous striatal dopamine ( DA ) transporter with GBR-13098 in mice has been shown to prevent damage to the DA nerve terminals caused by malonate.
44.
The nigro-striatal pathway originates from SNpc and irradiate its principal rostral target, the Caudate-Putamen ( CPu ) through the median forebrain bundle ( MFB ).
45.
It has been suggested that the VGKC antibodies may cross the blood brain barrier and act centrally, binding predominantly to thalamic and striatal neurons causing encephalopathic and autonomic features.
46.
Editing in some striatal and cortical neurons is more likely to be subject to excitotoxicity, thought to be due to less than 100 % editing of these particular neurons.
47.
When movement adjustment is required, striatal inhibitory GABAergic axons are sent to the "'lateral globus pallidus, "'decreasing inhibition of the subthalamic nucleus.
48.
Current understanding of brain anatomy and physiology suggests that striatal neural plasticity is what allows basal ganglia circuits to communicate between structures and to functionally operate in procedural memory processing.
49.
This degeneration of striatal neurons projecting to GPe leads to disinhibition of the indirect pathway, increased inhibition of STN, and therefore, reduced output of the basal ganglia.
50.
Increases in neuronal levels of DOPAC, a metabolic breakdown product of dopamine, have been shown to occur in striatal isolated nerve endings as a result of exposure to vinpocetine.
