dioxygenase वाक्य
उदाहरण वाक्य
मोबाइल
- The catalytic activity of gamma-butyrobetaine dioxygenase can be stimulated with different metal ions, especially potassium ions.
- Tryptophan 2, 3-dioxygenase was initially discovered in the 1930s and is found in both eukaryotes and prokaryotes.
- It has been shown that tryptophan 2, 3-dioxygenase is expressed in a significant proportion of human tumors.
- In the same study, tryptophan 2, 3-dioxygenase expression by tumors prevented their rejection by immunized mice.
- Inhibition of indoleamine 2, 3-dioxygenase, a target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.
- Several " in vitro " biochemical assays have been applied to monitor the catalytic activity of gamma-butyrobetaine dioxygenase.
- The enzyme belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage.
- Normally, the breakdown of the amino acid tyrosine involves the conversion of 4-hydroxyphenylpyruvate to homogentisate by 4-Hydroxyphenylpyruvate dioxygenase.
- Top : FAD-dependent amine oxidase mechanism of lysine demethylation Bottom : Fe ( II ) and ?-ketoglutarate-dependent dioxygenase
- Another study showed that tryptophan 2, 3-dioxygenase is potentially involved in the metabolic pathway responsible for anxiety-related behavior.
- Both modifications are catalyzed by the dioxygenase Asp / Asn-beta-hydroxylase, and are unique to EGF domains in eukaryotes.
- Hence blocking the oxidation of 3, 4-DHSA by the extradiol dioxygenase enzyme may be useful in the treatment of tuberculosis.
- Several hydroxylase enzymes are believed to incorporate an NIH shift in their mechanism, including 4-hydroxyphenylpyruvate dioxygenase and the tetrahydrobiopterin dependent hydroxylases.
- Iron is a 2OG oxygenases, the activity of gamma-butyrobetaine dioxygenase can be stimulated by reducing agents such as ascorbate and glutathione.
- Alkaptonuria is caused when an enzyme called homogentisic dioxygenase ( HGD ) is faulty so can't break down homogentisic acid ( HGA ).
- Meldonium is used for the treatment of angina and myocardial infarction by inhibiting the carnitine biosynthesis pathway via the inhibition of gamma-butyrobetaine dioxygenase.
- The enzyme that 2, 4'- dihydroxyacetophenone dioxygenase transforms 2, 4'- dihydroxyacetophenone and O 2 into 4-hydroxybenzoate and formate.
- Oxygen is not only a physiological requirement, but serves as a reactant in the hydroxylation of both aliphatic and aromatic hydrocarbons via monooxygenase and dioxygenase enzymes.
- Another theory developed more recently ( 2009 ) suggests that a NO dioxygenase activity could also proceed through phenolic nitration via a putative heme-peroxynitrite intermediate.
- COX-2 inhibitors down-regulate indoleamine 2, 3-dioxygenase, leading to a reduction in kynurenine levels as well as reducing proinflammatory cytokine activity.
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