hexokinase वाक्य
उदाहरण वाक्य
मोबाइल
- The enzyme hexokinase phosphorylates a six-carbon sugar, most notably glucose, which is the first step in glycolysis.
- Glucokinase ( GK ) is a hexokinase isozyme, related kinetic properties allow it to serve a different set of functions.
- Some other examples of enzymes are phosphofructokinase and hexokinase, both of which are important for cellular respiration ( glycolysis ).
- Glucose-1, 6-bisphosphate inhibit hexokinase stopping the production glucose-6-phosphate from D-glucose.
- More precise blood glucose measurements are performed in a medical laboratory, using hexokinase, glucose oxidase, or glucose dehydrogenase enzymes.
- The product s inhibition of hexokinase and activation of PFK-1 and pyruvate kinase is indicative of its role in glycolysis.
- "' Hexokinase "'is the most common enzyme that makes use of glucose when it first enters the cell.
- During World War II he worked on government-assigned crystallization projects and was noted for the facility with which he crystallized hexokinase.
- In glycolysis, hexokinase is directly inhibited by its product, glucose-6-phosphate, and pyruvate kinase is inhibited by ATP itself.
- In addition hexokinase and glucokinase act independently of the hormonal effects as controls at the entry points of glucose into the cells of different tissues.
- Hexokinase ( HK ) is the first enzyme in the glycolytic pathway converting glucose to glucose-6-phosphate through an ATP-dependent phosphorylation event.
- For example, hexokinase, an enzyme which catalyses the first step of glycolysis ( turning glucose into glucose 6-phosphate ), catalyzes the reaction in said direction.
- Under low oxygen conditions known as hypoxia, a small amount of TIGAR travels to the mitochondria and increases the activity of Hexokinase 2 ( HK2 ) by binding to it
- The hexokinase enzyme has a low Km, indicating a high affinity for glucose, so this initial phosphorylation can proceed even when glucose levels at nanoscopic scale within the blood.
- Hexokinase IV is present in the liver, pancreas, hypothalamus, small intestine, and perhaps certain other neuroendocrine cells, and plays an important regulatory role in carbohydrate metabolism.
- In this case, phosphoglucomutase catalyzes the conversion of glucose 6-phosphate ( which is easily generated from glucose by the action of hexokinase ) to glucose 1-phosphate.
- Due to the crucial role of HK1 in glycolysis, hexokinase deficiency has been identified as a cause of erythroenzymopathies associated with hereditary non-spherocytic hemolytic anemia ( HNSHA ).
- Increased expression of hexokinase 2, in some cases nearly 10-fold, allows for an increased flux of glucose through the glycolytic pathway subsequent to the increased uptake by GLUT1.
- In patients with essential fructosuria, metabolism of fructose by hexokinase to fructose-6-phosphate is the primary method of metabolizing dietary fructose; this pathway is not significant in normal individuals.
- His experience in the areas of glucose-6-phosphate biochemistry, carbon dioxide fixation, hexokinase and phosphate studies led him to hypothesize cotransport of glucose along with sodium through the intestine.
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