pleiotropic वाक्य
उदाहरण वाक्य
मोबाइल
- As might be expected of an enzyme involved in regulating NO levels and signaling, pleiotropic effects are observed in GSNOR knockout models.
- Interleukin 13 ( IL-13 ) is a pleiotropic cytokine that may be important in the regulation of the inflammatory and immune responses.
- Because the receptor gene is expressed in several forms, it has many different ( pleiotropic ) effects in different parts of the body.
- Interleukin 6 ( IL6 ) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response.
- Inhibition of IMPA1 activity can have pleiotropic effects on cellular function, including altering phosphoinositide signalling, autophagy, apoptosis, and other effects.
- "K " n also has other pleiotropic effects, as a reduction in comb size and hypertrophy of the uropygial gland.
- GCs have many diverse ( pleiotropic ) effects, including potentially harmful side effects, and as a result are rarely sold over the counter.
- Mice lacking functional copies of all three family members display pleiotropic phenotypes including exencephaly, edema, failures in neurite formation, and embryonic lethality.
- This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction.
- If an ancestral gene is pleiotropic and performs two functions, often neither one of these two functions can be changed without affecting the other function.
- These genes are ancient, being pleiotropic reuse explains why these genes are highly conserved, as any change would have many adverse consequences which natural selection would oppose.
- The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication.
- In all, thousands of genes are activated by TLR signaling, and collectively, the TLRs constitute one of the most pleiotropic yet tightly regulated gateways for gene modulation.
- Lethal white syndrome has been described by researchers as both pleiotropic conditions, such as lethal white syndrome, the application of " recessive " or " dominant " can be ambiguous.
- It is a highly pleiotropic disorder that clinically manifests by form of short-limbed dwarfism due to skeletal dysplasia, variable level of immunodeficiency and predisposition to malignancies in some cases.
- Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system.
- :: Yes, I suspect it's a pleiotropic effect, it is probably a side effect of the fact that the person has lots of body hair for some reason.
- NFAT is a transcription factor that activates the transcription of a pleiotropic set of genes, most notable, IL-2, a cytokine that promotes long-term proliferation of activated T cells.
- FGL2 is a protein that exhibits pleiotropic effects within the body and is an important immune regulator of both endothelial cells and can be constitutively secreted by both CD4 + and CD8 + T cells.
- Andrzej Pkalski, from the University of WrocBaw, argues that eugenics can cause harmful loss of genetic diversity if a eugenics program selects for a pleiotropic gene that is also associated with a positive trait.
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