kallikrein वाक्य
उदाहरण वाक्य
मोबाइल
- More than a dozen peptides and other substances have been isolated from the Gila monster's venom, including hyaluronidase, serotonin, phospholipase A 2, and several kallikrein-like glycoproteins responsible for the pain and edema caused by a bite.
- In the past, HMWK has been called HMWK-kallikrein factor, Flaujeac factor ( 1975 ), Fitzgerald factor ( 1975 ), and Williams-Fitzgerald-Flaujeac factor,-the eponyms being for people first reported to have HMWK deficiency.
- The B 2 receptor forms a complex with angiotensin converting enzyme ( ACE ), and this is thought to play a role in cross-talk between the renin-angiotensin system ( RAS ) and the kinin-kallikrein system ( KKS ).
- Upon binding to clots, or to the cell surface, plasminogen adopts an open form that can be converted into active plasmin by a variety of enzymes, including tissue plasminogen activator ( tPA ), urokinase plasminogen activator ( uPA ), kallikrein, and factor XII ( Hageman factor ).
- "' High molecular weight kininogen "'( "'HMWK "'or "'HK "') is a circulating plasma protein which participates in the initiation of blood coagulation, and in the generation of the vasodilator bradykinin via the Kallikrein-kinin system.
- Clements organised the 2 International Meetings : the 6th annual International Symposium on Kallikreins and Kallikrein-Related Peptidases ( ISK 2015 ), held in Brisbane, Australia from 28 September 1 October 2015, and the 9th General Meeting of the International Proteolysis Society, held in Penang, Malaysia from 4 5 October 2015.
- As well as expanding the company's pipeline with a late-stage treatment candidate for infectious conjunctivitis with lead candidate FST-100 and increased the companies rare disease catalogue with Dyax s portfolio of plasma kallikrein inhibitors against hereditary angioedema ( led by the approved drug Kalbitor and the Phase III DX-2930 ).
- In hereditary angioedema, bradykinin formation is caused by continuous activation of the complement system due to a deficiency in one of its prime inhibitors, C1-esterase ( aka : C1-inhibitor or C1INH ), and continuous production of kallikrein, another process inhibited by C1INH . This serine protease inhibitor ( serpin ) normally inhibits the association of C1r and C1s with C1q to prevent the formation of the C1-complex, which-in turn-activates other proteins of the complement system.
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