The'virino hypothesis'postulates that the TSE agent is a foreign, self replicating nucleic acid or nucleic acid fragment bound to PrP.
2.
Recalling Enrico Fermi's word play on a neutron-like particle, Outram coined the term'virino'to describe a small virus.
3.
Moreover philologists Vittor Pisani and Emile Benveniste have proposed a likely etymology for Vofiono-that makes it the equivalent in meaning of * Co-virino : Leudhyo-no.
4.
The virino also has the benefit of explaining the traits of TSEs which resemble nucleic acids : for example, their occurrence in strains, which positively indicates the TSE agent is information carrying, and not merely a toxin.
5.
In the virino model, the host protein protects the scrapie agent nucleic acids from degradation and prevents the host from raising an immune response, since the protein / nucleic acid complex is seen as a legitimate part of the host.
6.
The "'virino "'is a infectious particle that was once theorized to be the cause of scrapie and other degenerative diseases of the central nervous system; it was thought to consist of nucleic acids in a protective coat of host cell proteins.
7.
This hypothesis is confirmed by the fact that the two first god names at Iguvium are identical to their Roman counterpart ( Jov-and Mart-) and grammatically were nouns, whereas name Vofiono-is an adjectival derivation in " no-" of a noun root, just as * Co-virino.
परिभाषा
(microbiology) a hypothetical infectious particle thought to be the cause of scrapie and other degenerative diseases of the central nervous system; consists of nucleic acid in a protective coat of host cell proteins
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