| 1. | Gelatinase B may play an important role in angiogenesis and neovascularization.
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| 2. | This enzyme is similar to gelatinase A, but possesses a further domain.
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| 3. | Caseinolytic and gelatinase activities are normally present.
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| 4. | Slough, southeast England-based Celltech has patented a number of inhibitors of human gelatinase.
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| 5. | Effects of Enterococcus faecalis fsr genes on production of gelatinase and a serine protease and virulence.
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| 6. | For example, gelatinase B appears to be involved in the remodeling associated with malignant glioma neovascularization.
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| 7. | When interacting with TGF-?, Gelatinase B also stimulates collagen contraction, aiding in wound closure.
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| 8. | Gelatinase B has been found to be associated with numerous pathological processes, including immunologic and vascular diseases.
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| 9. | Elevated gelatinase B levels can also be found in the cases of rheumatoid arthritis and focal brain ischemia.
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| 10. | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family.
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