The medical regime, being married to a depletive or antiphlogistic physic until the early nineteenth century, Despite a declining intellectual foundation, the humoural-based medical practices of depletion and purgation, later called antiphlogistic ( anti-inflammatory ) therapy, had undergone little change since the time of Galen in the second century AD . Under this tradition, challenged increasingly from the seventeenth century, physical and mental health was dependent upon the maintenance of a proper balance between the four bodily humours of blood, phlegm, black bile and yellow bile ( choler ).
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