| 1. | In these cases, ACTH levels remain low and no hyperpigmentation develops.
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| 2. | Affected dogs can suffer from red hyperpigmentation, lichenification, and hair loss.
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| 3. | Improvement in skin hyperpigmentation is typically seen within six months when used twice daily.
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| 4. | Hydroquinone is ineffective for hyperpigmentation affecting deeper layers of skin such as the dermis.
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| 5. | Hyperpigmentation of the skin occurs in almost half; some also have skin nodules.
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| 6. | The most common is non-specific hyperpigmentation.
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| 7. | LET resolves with normal skin, no residual scarring, no hyperpigmentation or hypopigmentation.
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| 8. | It demonstrates hyperpigmentation of the colon with white lymph nodes showing through on colonoscopy.
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| 9. | If they do not receive treatment, the affected sites may develop permanent hyperpigmentation or hypopigmentation.
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| 10. | "Hyperchromia " can refer to hyperpigmentation, and " hypochromia " can refer to hypopigmentation.
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