| 1. | During development, the human DNA methylation profile experiences dramatic changes.
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| 2. | His test detects epigenetic modifications, in particular, DNA methylation.
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| 3. | Methylation, along with histone modification, is central to imprinting.
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| 4. | The S subunit determines the specificity of both restriction and methylation.
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| 5. | DNA methylation may affect the transcription of genes in two ways.
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| 6. | Thioflavin S results from the methylation of dehydrothiotoluidine with sulfonic acid.
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| 7. | Many cancers arise from the inappropriate epigenetic effects of misregulated methylation.
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| 8. | This happens through the transsulfuration pathway and the methylation of homocysteine.
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| 9. | Some miRNAs also undergo methylation-associated silencing in cancer cells.
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| 10. | Also, aberrant methylation patterns are well characterized in many cancers.
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