myelosuppression वाक्य
उदाहरण वाक्य
मोबाइल
- Excessive levels of 6-MP can cause myelosuppression and myelotoxicity.
- Myelosuppression more commonly occurs in CML patients and includes : thrombocytopenia and neutropenia.
- Unlike other nitrogen mustards, estramustine phosphate seldom produces significant hematologic toxicity such as myelosuppression,
- IG reversed cyclophosphamide-induced myelosuppression in tumor-bearing animals and enhanced survival rate.
- The effect of recombinant human granulocyte-macrophage colony stimulating factor on chemotherapy-induced myelosuppression.
- These anticancer drugs have, however, some limitations due to side effects, principally myelosuppression and neurotoxicity.
- It can cause the symptoms of diarrhoea and myelosuppression experienced by ~ 25 % of the patients administered irinotecan.
- GM-CSF has been compared to G-CSF as a treatment of chemotherapy-induced myelosuppression / Neutropenia.
- Chemotherapy can cause myelosuppression and unacceptably low levels of white blood cells ( neutropenia ), making patients susceptible to infections and sepsis.
- However, doxorubicin is associated with side effects such as myelosuppression, gastrointestinal disorders, mucositis, stomatitis, cumulative cardiotoxicity and extravasation.
- Thiotepa main toxicity is myelosuppression ( bone marrow depression ), which is the most serious complication of excessive therapy, causing leukopenia, thrombocytopenia, and anemia.
- It is a first-in-class, innovative treatment regimen designed to address unmet needs associated with solvent-based paclitaxel such as hypersensitivity reactions, increased myelosuppression and axonal degeneration.
- Defects in the TPMT gene leads to decreased methylation and decreased inactivation of 6MP leading to enhanced bone marrow toxicity which may cause myelosuppression, anemia, bleeding tendency, leukopenia & infection.
- Those with partial or complete DPD deficiency have a significantly increased risk of severe or even fatal drug toxicities when treated with fluoropyrimidines; examples of toxicities include myelosuppression, neurotoxicity and hand-foot syndrome.
- While too low of a dosage is simply ineffective, too high of a dosage can cause various toxic effects including pancreatitis, hepatotoxicity, and myelosuppression ( reduction in the ability to produce blood cells ).
- This results in the most common side-effects of chemotherapy : myelosuppression ( decreased production of blood cells, hence also immunosuppression ), mucositis ( inflammation of the lining of the digestive tract ), and alopecia ( hair loss ).
- However, atovaquone may be used in patients who cannot tolerate, or are allergic to, sulfonamide medications such as TMP-SMX . In addition, atovaquone has the advantage of not causing myelosuppression, which is an important issue in patients who have undergone bone marrow transplantation.
- Serious side effects included severe myelosuppression ( suppressed activity of bone marrow, which is involved in formation of various blood cells [ found in 98 % of patients ] ), disorder of the respiratory system, tumor lysis syndrome, Type III hypersensitivity, venous occlusion, and death.
- Certain genetic variations within the TPMT gene can lead to decreased or absent TPMT enzyme activity, and individuals who are homozygous or heterozygous for these types of genetic variations may have increased levels of TGN metabolites and an increased risk of severe bone marrow suppression ( myelosuppression ) when receiving azathioprine.
- Certain genetic variations within the TPMT gene can lead to decreased or absent TPMT enzyme activity, and individuals who are homozygous or heterozygous for these types of genetic variations may have increased levels of TGN metabolites and an increased risk of severe bone marrow suppression ( myelosuppression ) when receiving mercaptopurine.
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