| 1. | It is somewhat similar to penicillamine in both chemistry and pharmacology.
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| 2. | These are penicillamine, corticosteroids, calcium channel blockers, and ACE inhibitors.
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| 3. | In children, the penicillamine test may be used.
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| 4. | Examples of such drugs include sulphasalazine, chloroquine, penicillamine, gold and methotrexate.
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| 5. | Generally, penicillamine is the first treatment used.
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| 6. | It is unclear whether these people are best treated with penicillamine or zinc acetate.
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| 7. | Penicillamine has been used in rheumatoid arthritis since the first successful case in 1964.
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| 8. | A 500 mg oral dose of penicillamine is administered, and urine collected for 24 hours.
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| 9. | Some recommend trientine as first-line treatment, but experience with penicillamine is more extensive.
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| 10. | HCQ can increase plasma concentrations of penicillamine which may contribute to the development of severe side effects.
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