topoisomerase वाक्य
उदाहरण वाक्य
मोबाइल
- Topotecan inhibits topoisomerase I restoring UBE3A levels to wild-type range in cultured mince neurons.
- Many topoisomerase enzymes sense supercoiling and either generate or dissipate it as they change DNA topology.
- The proper function of RecQ helicases requires the specific interaction with topoisomerase III ( Top 3 ).
- The study suggested that the topoisomerase inhibitors have the potential to produce a normally functioning UBE3A protein.
- Additionally, topoisomerase II has been implicated in the regulation of Aurora B localization and enzymatic activity.
- Topoisomerase I is an enzyme that mediates reversible single-strand breaks in DNA during DNA replication.
- Some chemotherapy drugs called topoisomerase inhibitors work by interfering with mammalian-type eukaryotic topoisomerases in cancer cells.
- EGCG, genistein, quercetin, resveratrol ) possess strong topoisomerase inhibitory properties affecting both types of enzymes.
- Topoisomerase IV in " E . coli " unlinks or decatenates the two circular DNA duplexes.
- They are also referred to as anti-DNA topoisomerase I antibody ( anti-topo I ).
- This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta.
- Fourth generation fluoroquinolones act at DNA gyrase and topoisomerase IV . This dual action slows development of resistance.
- Professor Austin's published research is focused on human DNA topoisomerase II and therapy-related leukemia.
- Fourth-generation fluoroquinolones act at DNA gyrase and topoisomerase IV . This dual action slows development of resistance.
- Anti-topoisomerase antibodies can be classified according to their immunoglobulin class ( IgM, IgG or IgA ).
- The article Camptothecin lists other analogues of camptothecin and the article Topoisomerase inhibitor lists other compounds which inhibit TOP1.
- Her most cited article, CA Austin, KL Marsh . " Eukaryotic DNA topoisomerase II? " in"
- Hycamtin, approved in May 1996, is a new type of cancer drug known as a topoisomerase I inhibitor.
- Nalidixic acid and related antibiotics inhibit a subunit of DNA gyrase and topoisomerase IV and induce formation of cleavage complexes.
- Amsacrine also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II ( compares with the better known agent etoposide ).
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