| 1. | Topoisomerase IIA plays an essential role in resolving these topological problems.
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| 2. | Topoisomerase I and SR proteins also interact to increase genome stabilization.
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| 3. | They act as anti-cancer drugs by inhibiting topoisomerase II.
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| 4. | Some organisms have two isoforms of topoisomerase II : alpha and beta.
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| 5. | Topoisomerase poisons have been extensively used as both anticancer and antibacterial therapies.
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| 6. | Cadmium cations react with the topoisomerase in the following manner:
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| 7. | The topo I of both prokaryotes and eukaryotes are the type I topoisomerase.
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| 8. | CcdB protein is a topoisomerase poison from " Escherichia coli ".
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| 9. | Topoisomerase inhibitors can also function as antibacterial agents.
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| 10. | Also, cells deficient in topoisomerase II show significantly reduced Aurora B kinase activity.
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