For example, the drug pioglitazone contains a thiazolidine ring.
2.
Hydrolysis of the thiazolidine generates the thiol and aldehyde or ketone from which it was synthesized.
3.
"' Rhodanine "'is a 5-membered heterocyclic organic compound possessing a thiazolidine core.
4.
"' Thiazolidine "'is a heterocyclic organic compound with a 5-membered analog of oxazolidine.
5.
It lowers blood pressure and increases levels of HDL . Another drug which contains a thiazolidine ring is the antibiotic drug penicillin.
6.
A second hydrogen transfer occurs, most likely producing an isopropyl radical which closes the thiazolidine ring by attacking the thiolate sulfur atom.
7.
The coupling of amino acid derivatives to a growing peptide chain containing N-terminal pseudoproline generally results in low yields because of the sterically hindered nature of the oxazolidine ( thiazolidine ) ring system and the decreased nucleophilicity of the nitrogen atom.
8.
Tidiacic arginine ( trade name "'Tiadilon "') is a 1 : 1 combination of the amino acid arginine and tidiacic ( thiazolidine-2, 4-dicarboxylic acid ), which acts as a sulfur donor.
9.
Two conceptually different approaches are feasible for preparing oxazolidine-and thiazolidine-ring-containing dipeptide derivatives : ( 1 ) the in situ acylation of Ser-or Thr-derived oxazolidines or Cys-derived thiazolidines using acid fluorides or N-carboxyanhydrides ( NCA ); and ( 2 ) the direct insertion of the oxazolidine systems into dipeptides ( post-insertion ) containing C-terminal Ser or Thr.
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